Found 9 matching trials
Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults PHASE1 This is a randomized, double blind, placebo-controlled, single site, trial ...
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Fred Hutchinson Cancer Research Center
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A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI PHASE1 USSPZV7 is a randomized, phase 1, double-blind, placebo-controlled trial of...
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University of Maryland, Baltimore, Center for Vaccine Development and Global Health
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A Clinical Trial of the PfSPZ Vaccine Administered by Direct Venous Inoculation in Healthy Malaria-Naïve Adults: Heterologous vs. Homologous Controlled Human Malaria Infection and Reduction in Number of Doses PHASE1 This is an open-label evaluation of the safety, tolerability immunogenicity...
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Walter Reed Army Institute of Research (WRAIR) Clinical Trials Center
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A Clinical Trial to Evaluate Plasmodium Falciparum 7G8 and NF54 Challenge Strains (PfSPZ) in a Head-to-head Comparative Study - (ECG-CHMI) NA A comparison of Malaria events (symptoms and signs of malaria) experienced ...
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Multiple Locations
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First-in-Human PfSPZ-LARC2 Vaccination/CHMI PHASE1 This randomized, double-blind, placebo-controlled, Phase 1 trial will enrol...
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The University of Washington - Virology Research Clinic
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Dose Escalation PfSPZ-CVac PHASE1 Background:
People get malaria from bites from infected mosquitos. Researc...
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National Institutes of Health Clinical Center
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PfSPZ Vaccine: Dose Optimization With Heterologous Challenge in Healthy Malaria-Naïve Adults PHASE2 This is an open-label evaluation of the safety, tolerability, immunogenicit...
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University of Maryland-Baltimore, Center for Vaccine Development
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Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis PHASE2 This is an open label, Phase 2 study with controlled human malaria infectio...
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Clinical Research Unit, Uniformed Services University of Health Sciences
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Sequential Optimization of Dose and Schedule of PfSPZ Vaccine PHASE1 MAVACHE is a sequential dose and schedule optimization trial of intravenous...
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Institute of Tropical Medicine, University of Tuebingen, Wilhelmstr. 27
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